14 comments

  • goodmythical 2 hours ago
    What I've never understood is the weird dichotomy of preventive and reactive governance in the minds of US citizens.

    We're willing to spend god knows what shooting rounds that cost entire mortgages to save miltary lives and project a presence of power to deter acts of terror/war, but then are also totally fine having people way as much as 4 or 5 people, eating several days worth of sugar for breakfast, smoking tobacco, putting 3 cups of coffee in a can we drink 4 or five of in a day, do next to nothing to adress recidivism of all classes of criminal, drag our feet kicking and screaming in to a semblance of modernity in worker protections...

    • hibikir 57 minutes ago
      In some ways, US healthcare is already very aggressive for some forms of preventive medicine. Compare the colon cancer protocols across the world. Basically nobody else is recommending colonoscopies to the entire population with no cheaper tests, but that's the standard of care in the US. It's not free to receive, and it's expensive in general, but for some reason in the US it is standard, instead of starting with non-invasive tests.

      And yes, regarding smoking, the US has had one of the most effective preventive actions in the world. Compare actual numbers of smokers in the US vs, say, Spain, France or Turkey. So it's not anywhere near as clear cut as what you are trying to make it sound.

      • Nomadeon 19 minutes ago
        Walk into a US gastro with a hang nail and you'll walk out with a colonoscopy requisition.

        They make money on the procedure, not the office hours. And they write the standards of care.

        That being said, my father delayed a screening, developed colon cancer, and now no longer has a colon. Would cheaper / higher compliance tests have caught it sooner? Hard to say.

      • teachrdan 9 minutes ago
        > Basically nobody else is recommending colonoscopies to the entire population with no cheaper tests

        I'm not sure if I understand what you're saying. Kaiser Permanente sends me a take-at-home colonoscopy test every year, and some light googling suggests the cost is $20-$89. I've never done an in-person colonoscopy, but the home version must be cheaper, right?

      • buellerbueller 5 minutes ago
        Hypothesis: The American diet contains more carcinogens (dyes, additives, pesticides, supplements in poultry/beef/pork) and therefore USA is is more need of CRC screening.

        USA generally high her rates than other developed nations.

        https://pmc.ncbi.nlm.nih.gov/articles/PMC2796096/

        the screenings may make sense, here

    • stetrain 1 hour ago
      > smoking tobacco

      There actually has been a really big push against this in the US. I was shocked by the amount of smoking I saw on a recent trip through Northern Europe, whereas smoking in public is pretty rare to see in the US these days.

      Now we just vape our nicotine directly, or smoke weed, depending on the state.

      • StableAlkyne 1 hour ago
        Cigarettes have definitely gotten a trashy vibe in the US. It's kinda nuts how fast we went from smoking sections in fast food restaurants just 30 years ago to even bars banning it. In college 10 years ago, the only people I knew who regularly smoked cigarettes were from Europe, China, and India.

        Cigars are still cool though, but those have always been the higher status tobacco due to the cost per stick. Also most people don't go through public spaces smoking a cigar, so it doesn't have the annoyance factor of vapes. Hookah still has a fun vibe too, probably because of the social factor.

      • vonnieda 51 minutes ago
        Can you say where in the US you find it rare to see smoking in public? I live in Kansas City and have been in Vegas, Seattle, and NYC recently and there is plenty of smoking everywhere. Less than the 80s, sure, but certainly not rare.
        • OkayPhysicist 18 minutes ago
          How recently were you in Vegas? I was blown away by how little smoking there was post pandemic even compared to 2018. Like, most casinos no longer reek of cigarette smoke. I'm sure that's partly explained by better air circulation installed to reopen sooner post-COVID, and probably taking the closures as an opportunity to replace some seriously steeped carpet, but the amount of smoking was way, way down. It used to be if you saddled up to craps table, at least one, if not two people would be actively smoking. Now you can look around the entire pit and not even see one. The combination of anti-smoking measures in broader society, and the uptake of vaping has wildly reduced the amount of smokers. We're talking a 60% reduction since 2000, and that was after the trend was already heading that direction.

          Compare that to most places internationally, and the contrast is stark. The US has less than half the cigarette consumption per capita than the EU, with only the U.K., Norway, and Sweden having lower rates. China has a similar rate to the EU.

          Just to drive that point home a little harder, the state with the highest number of smokers is West Virginia, sitting at 21% (the national average is 9.6%). That would be middle of the pack in Europe, similar to Italy.

          • vonnieda 1 minute ago
            I was in Vegas in August for Def-Con and there was a ton of smoking. Our hotel’s casino/lobby was disgusting. The smokers area outside the convention was plenty busy. Walking to the monorail there were people outside most hotel back doors smoking.

            Which reminds me: Also, the smoking area of every airport I’ve been to in the last 2 years has been thick with smokers.

            I know it’s better than the 80s. I was there. But I don’t think it’s rare in the US at all.

        • dghlsakjg 20 minutes ago
          I think this is a case of rare being relative to the past.

          In the 90s and earlier it was hard to be in a city and not be breathing cigarette smoke pretty much constantly. Offices had ashtrays in the elevator waiting areas for people who couldn't wait to get to their office, restaurants had half the seating reserved for smokers, there were ashtrays in the armrest of every single seat on an airplane.

          Its kind of crazy how much norms have changed around smoking in public. It's not "rare" to see a smoker, its that it is much rarer than it was in the past.

        • raddan 22 minutes ago
          Rare in the northeast US. In fact, I saw two students smoking on a college campus just last week and did a double take. I had not seen a single student smoking in at least a decade. Then I laughed remembering how when I was in college in the 90s, almost everybody smoked at least a little (often at parties), and seeing students smoking at the entrance to the dorm was pretty normal. I am an asthmatic so I've never smoked, and I remember my friends being stunned by this one night when we were out at a bar. Things have changed a lot around here.
        • spiffyspleen 34 minutes ago
          Idk if it would call it rare because yeah going on a walk in a downtown area you will definitely see at least a couple people smoking. But 30 years ago it seemed like every other person you passed on the sidewalk was smoking.
        • stetrain 45 minutes ago
          Rare as in you can absolutely spot a person smoking sometimes, but there is not the perception that everyone is smoking, the air does not always smell like cigarettes on the streets and even inside businesses, and the ground is not covered in cigarette butts everywhere.

          NYC vs Hamburg, Amsterdam, or Brussels are night-and-day differences on this point.

          I'm not sure Vegas is representative of much of anything, but last time I was there what I smelled was weed, not tobacco.

          • vonnieda 40 minutes ago
            In my daily life, every day, I am behind cars with people smoking, see people on their smoke breaks outside the doors of offices and retail, walk behind people on the sidewalk smoking, and see it on basically every job site I pass.

            I only bring this up because I keeping seeing people say it's "rare" in the US, but is something rare if you run into multiple times every single day?

            • Projectiboga 20 minutes ago
              The price of cigarettes varies widely around the US, which may affect demand. Though I thought VA is a tobacco state.
          • richwater 19 minutes ago
            I loved Amsterdam but the amount of litter, composed mostly of cigarette butts was eye-opening.
        • wat10000 34 minutes ago
          DC suburbs here, I can’t remember the last time I saw someone smoking.
    • rayiner 1 hour ago
      Implementing solutions to prevent future harms is tricky and requires understanding systems we often don’t understand very well. For example with healthcare, people say that preventative medicine will reduce costs in the long run. But studies show that isn’t really true: https://jamanetwork.com/journals/jama-health-forum/fullartic.... Preventative care can improve health outcomes at higher cost, but the cost of the programs outweighs any savings from avoided costs later.
      • arjie 29 minutes ago
        In the limit, one would expect that to be the case: at some point the marginal cost curves will intersect. I’m quite surprised that we are already at that point. I suppose more things are at the efficiency frontier than I had imagined.

        Thanks for the link. Will have to read it later.

    • iamnothere 1 hour ago
      Because people are unable to conceptualize the idea of government-funded voluntary preventative campaigns, despite these showing success in the past.

      This may be partially due to the many all-or-nothing crusaders who would prefer to use force in their quest for full protection of the citizen. Many people overcorrect because they fear that even voluntary programs are steps in this direction. Trust is low.

      We have a long and sordid history with extreme and failed prevention (prohibition, the Mann Act, war on drugs).

    • danielmarkbruce 23 minutes ago
      The US is founded on the idea of individual freedom, and that one of the few areas of "collective" spending should be defense.

      This is 101. If you don't like it that's fine, but not understanding it can be resolved with a simple google search.

    • zamadatix 1 hour ago
      Much of the US doesn't think of it in terms of proactive vs reactive governance but instead in cultural/moral expectations of how you should "pull yourself up from your bootstraps" to be great. This view is often to the point many see removing the need to pull oneself up from their own bootstraps as removing the ability for them to better themselves (& wasting everyone else's money/freedom/whatever to do so). A soldier and an obese person are examples at polar opposites of that moral spectrum.

      The policies just follow that. This comes up in all sorts of areas such as prison as punishment vs rehabilitation.

      • somenameforme 1 hour ago
        I think you're looking at an effect instead of a cause. The main reason for the desire for a small government is not some inherent and absolute obsession with smallness, but because of the belief that larger governments are incapable of effectively utilizing their power (for reasons beyond just incompetence), are prone to inevitable abuses, and so forth. And that belief itself is not simply ideological, but based on history through most of all time.

        Even with rehab versus punishment - it's the same story. The view isn't that punishment is inherently superior, but simply that rehabilitation is more of an ideal than a reality, and that typical appeals to places like Norway - a relatively homogenous and extremely wealthy microstate - don't necessarily translate well to large diverse societies, especially ones where there are substantial chunks of society that adopt cultures that glorify criminality.

        • zamadatix 11 minutes ago
          I don't think there is a clear cause and effect (or even separation) of those two things. The early views/situations of those who made America are largely the same force which drove the desire for small government and vice versa. I.e. what you believe is ideal in reality is going to be based on the way you weigh things morally just as much as the way you weigh things is going to be based on what ideal is held.

          There is, of course, more than one reason people hold the views they do, but I do believe things like rugged individualism & the Protestant work ethic definitely played a major role in why the majority of Americans hold the desires and fears about government they do - particularly in the aspect of these examples. Without those influences, I think what America has tried vs what it has feared would be a very different list today (which is not to say whether it'd've been more successful or not).

        • devmor 1 hour ago
          My views on this subject are far too detailed to want to get into here, but I am confused at your choice to call Norway a "microstate". It's certainly on the smaller side of countries, but there are over 5 million residents and 300,000km2 in size. It's just a normal country.

          "Microstate" is a term generally reserved for tiny geographical locations that can't even support their own defense.

      • ElProlactin 1 hour ago
        From Kurt Vonnegut in Slaughterhouse-Five:

          America is the wealthiest nation on Earth, but its people are mainly poor, and poor Americans are urged to hate themselves. To quote the American humorist Kin Hubbard, 'It ain’t no disgrace to be poor, but it might as well be.' It is in fact a crime for an American to be poor, even though America is a nation of poor. Every other nation has folk traditions of men who were poor but extremely wise and virtuous, and therefore more estimable than anyone with power and gold. No such tales are told by the American poor. They mock themselves and glorify their betters. The meanest eating or drinking establishment, owned by a man who is himself poor, is very likely to have a sign on its wall asking this cruel question: 'if you’re so smart, why ain’t you rich?' There will also be an American flag no larger than a child’s hand – glued to a lollipop stick and flying from the cash register.
        
          Americans, like human beings everywhere, believe many things that are obviously untrue. Their most destructive untruth is that it is very easy for any American to make money. They will not acknowledge how in fact hard money is to come by, and, therefore, those who have no money blame and blame and blame themselves. This inward blame has been a treasure for the rich and powerful, who have had to do less for their poor, publicly and privately, than any other ruling class since, say Napoleonic times. Many novelties have come from America. The most startling of these, a thing without precedent, is a mass of undignified poor. They do not love one another because they do not love themselves.
        • true_religion 48 minutes ago
          To put it in context, the poor elsewhere were poor by class. No attempt to become rich was permissible by law so it was key that this supermajority of the population did not believe they were downtrodden, and unfairly opposed.

          Claiming the poor have more virtue, but only in their class status, is one way to do it.

          Consider how many caste systems claim the farmer is the highest status, the wisest, the most virtuously hard working … but well still needs a good noble king to lead them.

      • lokar 1 hour ago
        Everything is America is about race
        • bitmasher9 1 hour ago
          America does a better job at assimilating immigrants than most of the rest of the world. It’s just a very hard problem, and the US does more of it than anyone.
          • fnimick 1 hour ago
            Not everyone in this country who isn't white has ancestry from an immigrant (or at least not a willing one).
            • johnnyanmac 44 minutes ago
              I definitely wouldn't say my lineage had any call in "immigrating" into the US.

              And yes, don't underestimate how such maneuvers are very indirect means of white flight. African Americans could only (legally) own a home in much of the US for 50 years. At the very best, that is 2 generations of wealth to accrue, which puts that demographic a good century behind what potentially could have been economically.

              • wahern 12 minutes ago
                50 years would be 1976. Perhaps you're confusing it with the myth about women being legally prohibited from opening bank accounts. (1972 was when sex discrimination by businesses was outlawed at the Federal level, though there was never a law that prohibited a women from having a bank account, not directly, and not indirectly since the 1800s. Some banks discriminated against married women, but unless they lived in a one-bank town there were others that were happy to have their business.)
        • Avicebron 27 minutes ago
          This kind of thinking is how you get trump 3.0 after you blame and alienate people who want their lives to improve.
        • fnimick 1 hour ago
          I don't know why you got downvoted. If you don't believe this, read "Dying of Whiteness" by Jonathan Metzl. Something like 30% of this country will reject quality of life improvements for themselves if they see that it will also benefit people of other races who "don't deserve it".
          • lokar 1 hour ago
            The entire social structure of the south was (and mostly still is) based on wealthy whites convincing poor whites to accept the situation because blacks are even worse off.
            • digitaltrees 1 hour ago
              And those that haven’t lived in the south can’t comprehend that it really is the core animating belief behind the entire apparatus of government.
              • mrguyorama 2 minutes ago
                You shouldn't have to believe, because the various poor white guys who died for the south wrote plenty about how their driving motivation was that a black guy having the same social status as them was worse than death.

                They literally wanted to kill northerners for daring to make them equal to black people.

                Still do.

        • iamnothere 48 minutes ago
          *Everything in America is about class, with race as a frequent proxy for class

          Fixed that for you

          • johnnyanmac 40 minutes ago
            Judging by the color of one's skins is one of the easiest and oldest ways to discriminate. Only behind by the contents of one's genetalia. But the latter at least has a biological need to care for one another.

            It's a bit of a chicken and egg situation. At least when someone looks at someone who "looks like them" but is poorer, they see "potential" (there's a name for this effect, but I forget). But the end goal is getting theirs first and foremost.

            • iamnothere 23 minutes ago
              True, but this effect tends to diminish at the highest levels of wealth.

              At lower levels you have the “labor aristocracy” effect, which gives the more well-off workers a material stake in racism. And this division is useful to prevent organization.

              > the end goal is getting theirs first and foremost

              Seconded

            • oortoo 17 minutes ago
              Its also about language and colloquialisms. If you grow up poor, but go to a school with many wealthy children, you will learn to speak the "language" of the wealthy, which is, in my opinion, what mostly explains the "having potential" that the ruling class will see in your as you enter adulthood.
    • EGG_CREAM 1 hour ago
      It’s very strange to include caffeine in that list of unhealthy things. Everything else in that list is proven to be bad for society/health, except for caffeine. Why did you choose to highlight caffeine consumption when there is not really any evidence it causes health issues?
      • cogman10 55 minutes ago
        I don't think there's long term evidence for negative problems. However, high dosages of caffeine are dangerous and have killed people. Those dosages are easily achieved through the likes of energy drinks.
        • dghlsakjg 4 minutes ago
          Chronic long-term use of high amounts of caffeine (>600 mg, or two Starbucks Grande coffees) are linked with: bone density issues, sleep issues, anxiety issues, cardiovascular strain, stomach acid issues. They aren't super bad, but definitely not harmless.
        • malfist 44 minutes ago
          High dosage of water have also killed people. And easily achieved through energy drinks? I strongly doubt that. Most energy drinks are not any stronger than coffee
          • cogman10 24 minutes ago
            Lower dosages of caffeine kill you than the water dosages that kill you.

            > And easily achieved through energy drinks?

            Yeah, once you start pushing 1000mg of caffeine, you are getting into areas where if you have heart problems, you could be putting yourself in danger.

            > Most energy drinks

            But not all. So why strongly doubt it?

            There are plenty of energy drinks which are fairly popular with huge amounts of caffeine and there's little labeling requirements to let people know that. Bang energy drink is a good example of that. 300mg per can, meaning 3 cans is putting you in dangerous territories.

      • helsinkiandrew 56 minutes ago
        The comment said “putting 3 cups of coffee in a can we drink 4 or five of in a day” that would be 1,000–1,500 mg of caffeine. The FDA guidelines is 400mg a day and drinking 1200mg quickly can induce seizures
        • chasd00 17 minutes ago
          16 oz can of white monster (stereotypical energy drink) has about 150mg of caffeine. A grande (16 oz) black coffee from Starbucks has about 310mg of caffeine. You would need to drink 2 16 oz monsters to get the same amount of caffeine as a single grande cup of coffee from Starbucks.

          If you're just looking at caffeine intake you'd be better off switching from coffee to energy drinks. You could drink about 3 per day and be close to the 400mg/day guidance.

          edit: white monster has no sugar in case anyone was about to bring that up

          • zdragnar 10 minutes ago
            > If you're just looking at caffeine intake you'd be better off switching from coffee to energy drinks

            This is less true now than it used to be. I'm somewhat sensitive to caffeine and always look on the can to see how much is in it, and 150 is on the low side of most of the options available now-. 200 to 300 seems to be a lot more common among the brands that are newer than when monster and Rockstar first came out.

        • EGG_CREAM 44 minutes ago
          It’s included in a list of things bad for “ society/health.” While overconsumption on that level would certainly be a health issue for an individual, it doesn’t even register compared to the other things he lists as a social issue, like chronic obesity and Tobacco use. It’s just weird and misleading to include it in that list, is all I was pointing out.
      • johnnyanmac 53 minutes ago
        less the caffine itself and more the amount. It sounds like they are talking more about energy drinks or some highly concentrated espresso shot.

        I don't think that much caffeine is good for you, especially 4-5 times a day. But with everything else we gulp down it probably isn't priority #1.

        Tangential, but I suppose this is a good time to highlight how caffeine undisclosed can in fact kill some people:

        https://www.bbc.com/news/articles/c5y95yylxv7o

    • keiferski 1 hour ago
      Big assumption that the average citizen’s opinion has any effect on what the government spends money on. It’s pretty easy to campaign on not doing X and then proceed to do X once you’ve won the election.
      • rayiner 58 minutes ago
        If you keep in mind that the median voter in a primary is 65, then the government we have seems to do a pretty good job of reflecting the opinions of the politically engaged subset of the population.
    • calibas 57 minutes ago
      Overconsumption means enormous profits, that's the whole logic to it. Gotta keep numbers going up and shareholders happy.
    • swed420 2 hours ago
      > What I've never understood is the weird dichotomy of preventive and reactive governance in the minds of US citizens.

      When the underlying economic model of CONSUMPTION = GOOD is viewed as a religion or universal law of nature, it's actually not surprising that people are irrational about this.

    • wat10000 32 minutes ago
      I don’t entirely agree, but it’s not inconsistent. The idea is that government is supposed to protect you from bad guys (criminals or enemy countries) but it’s not their job to protect you from yourself. If somebody wants to shoot you, the government is supposed to stop them. If you want to eat an entire cake for lunch every day, that’s your own business.
    • jimt1234 1 hour ago
      In the US there's an extreme attitude of "I'm not paying for someone else...", and any sort of preventative care, like a heart score test, would fall into that category. This attitude is grounded on the personal responsibility mindset, that every person is responsible for taking care of themselves. So, for the 800K people that had heart attacks, the attitude in the US is largely, "They should've been proactive on their own, gotten the $100 test. Their heart attack is their own fault."
    • jmyeet 14 minutes ago
      It's because of racism. No, seriously.

      If something disproportionately affects black people negatively, it has a significant amount of support from certain voters. The whole origin of the anti-abortion movement in the 19th century was double-pronged to displace midwives (who were often minorities) and that too many white women were getting abortions, which was labelled "race suicide" [1].

      Need more? Infant mortality skews heavily by a state being red or blue and by the racial makeup [2]. Iowa is a red dot in a sea of blue because it's particularly white. Compare the US to other developed nations [3].

      So this particular issue is with heart disease. And guess what? Black people are disproportionately affected and have worse outcomes [4]. Shocking.

      Many people have a shallow view that racism is using slurs. It is not. Racism is systemic. And it's not as direct and nefarious as people in a smoke-filled room getting together to try and create worse heart disease outcomes for black people. It's a series of steps taken such that this problem isn't solved. It's just not prioritized.

      You see the same thing with medical misogyny and medical racism. Symptoms are downplayed and ignored. This has been thoroughly tested where doctors have been given a file genders changed and there are statistically different outcomes.

      [1]: https://sociology.northwestern.edu/documents/faculty-docs/fa...

      [2]: https://en.wikipedia.org/wiki/List_of_U.S._states_and_territ...

      [3]: https://www.americashealthrankings.org/publications/reports/...

      [4]: https://pmc.ncbi.nlm.nih.gov/articles/PMC9310198/

    • ThrowawayTestr 1 hour ago
      People being free to destroy their bodies with food has nothing to do with everything else you mentioned.
    • raz32dust 58 minutes ago
      It's easy to understand. US optimizes for whatever helps with more overall spending. They can print money and export inflation to others. All this new money then goes to the companies that hold power through lobbying.
    • 233mhz 1 hour ago
      > and project a presence of power to deter acts of terror/war

      uh? That's literally what causes terror and wars lmao

      • MaxHoppersGhost 1 hour ago
        While I agree the US meddling in the Middle East has caused wars/terrorism, the general US military presence globally is a massive benefit for the entire world. Once the US starts pulling back more (as they seem to want to do) we'll see more and more regional chaos that grows into trade disruptions and wars. Regional tomfoolery like the South China Sea stuff will occur all over the world and will escalate into wars.
        • 233mhz 1 hour ago
          > we'll see more and more regional chaos that grows into trade disruptions and wars

          Every accusation is a confession, as they say. How can you say this with a straight face given the current situation in Iran lol? They keep pulling the same shit and NPCs keep licking the boots, it's insane...

  • getpost 30 minutes ago
    Scripps cardiologist Eric Topol (not commenting on this article): "That's wrong. The CAC is anything but definitive. Many patients are told they have significant coronary artery disease by calcium score and it turns out, by CT angiography or cardiac catheterization, they have normal arteries. No less anxiety (often chronic and severe) and unnecessary procedures that are induced by false positive CACs." https://x.com/EricTopol/status/2092682606815117763

    Coronary calcium scans quantify calcified atherosclerotic plaque but cannot reliably distinguish stable plaques from rupture-prone plaques or detect noncalcified plaques, some of which may be particularly vulnerable.

    https://www.ahajournals.org/doi/pdf/10.1161/JAHA.118.008564

    https://www.jacc.org/doi/10.1016/j.jcmg.2017.03.005

    https://www.atherosclerosis-journal.com/article/S0021-9150(1...

    • nradov 13 minutes ago
      Eric Topol has some opinions. Some other cardiologists disagree. There probably is value in CAC for at least a subset of patients.

      In the messy real world of medicine there are hardly any definitive screening tests or imaging studies. Everything will have some false positives and false negatives, or even if the output is physiologically accurate it may not be practically useful in improving patient outcomes. For screening tests we also have to weigh the costs versus benefits in terms of the number of procedures performed or dollars spent to save a life; if the numbers are too high then those scarce resources should be expended on other healthcare services.

      For broad screening coverage by most health plans the key next step is an evaluation by the U.S. Preventive Services Task Force. This process is already underway but it takes a while for them to evaluate all the evidence and make a decision. For Medicare coverage there is a separate coverage determination process.

      https://www.uspreventiveservicestaskforce.org/uspstf/

      https://www.cms.gov/medicare/coverage/determination-process

    • inglor_cz 13 minutes ago
      On a similar personal note, I had a half-year health scare that ended just today.

      In May, they told me on ultrasound that my dilated aortic root has grown by more than 2 mm in the last year and that if the progression does not stop, an operation will sooner or later be necessary.

      I got a referral to magnetic resonance and had to wait for it until October. Was there last week, nervous. Today I got the result: compared to the MR from 2021, there is no progression at all. The same 44 mm as then. The ultrasound was just not as precisely done, or the doctor measured it slightly askew or what.

      Ooof.

  • brandonb 2 hours ago
    Coronary CT calcium scans are getting more popular. But before getting one, I'd do these simpler tests first:

    - ApoB - about 20% of people with normal cholesterol results will have abnormal ApoB, and be at risk of heart disease.

    - Lp(a) - the strongest hereditary risk factor for heart disease.

    - hs-CRP - inflammation roughly doubles your risk of heart disease

    - HbA1c - insulin resistance is a risk factor for just about everything.

    - eGFR - estimates the volume of liquid your kidneys can filter, and is an input to the latest heart disease risk models (PREVENT).

    These are simple blood tests. You can get them for <$200 through my company or others:

    https://empirical.health/product/comprehensive-health-panel

    Imaging is great for detecting calcified plaque in your coronary arteries. But before you have calcified plaque, the above risk factors tell you about the buildup of soft plaque. And 4 out of 5 of them are modifiable through lifestyle, exercise, and medication.

    • someguydave 2 hours ago
      But you know the result will be recommendations for diet, exercise and statins so why not skip the tests and just do those?
      • brandonb 2 hours ago
        A few reasons:

        - If you made a dietary change (e.g., more fiber and less saturated fat), the tests tell you whether it actually worked.

        - Statins are dosed based on the LDL or ApoB reduction you need. The most powerful statins cut cholesterol by 50%, but at higher doses the risk of side effects does go up.

        - Other medications like PCSK9 inhibitors and ezetimibe exist, and whether to use them depends on the other numbers. For example, PCSK9 inhibitors have a secondary benefit of lowering Lipoprotein(a), and statins and GLP-1s have a secondary benefit of lowering inflammation.

        - If blood pressure, HbA1c, etc is high, then there's a slightly different set of diet advice and a very different set of medications. For example, lowering blood pressure through diet is mostly about reducing sodium and increasing potassium.

      • hibikir 52 minutes ago
        Because for the same behavior, risks are going to be very different on the other side. In my family, for instance, we need significant interventions to get a reasonable risk due to all the bad genetic factors. In my wife's family, not so much. So knowing how serious the risk seems much better than just handing statins to absolutely everyone.
      • devin 41 minutes ago
        Behavioral changes can only do so much to lower ApoB. It is a meaningful marker and may trigger additional workup. It may also signal that you should at least consider a statin.

        ApoA is completely out of your control and will not change with behavioral modification.

        So, no, you're incorrect that these tests are superfluous and all you need to say is "diet and exercise". Besides, even if that was always the answer to these results, you should still have a baseline to see if behavioral modification is doing anything.

      • myersj 41 minutes ago
        "Why not just skip the HbA1c tests? After all, you know they'll give you insulin. Just start taking it."

        Do you think everyone with poor blood test indicators is aware of how unhealthy they are? How quickly they need to reverse course? Or do think there might be some possible validity to discussing your results with an actual doctor and understanding how acute your symptoms actually are? Do you think there are no side effects to statins and everyone should just be on one at all times, forever? Do you think there might be some value, for those patients, in discussing GLP-1s? Or nah, everyone can just like, go run 10 miles tomorrow because some 20 year old in SV said so?

        I'm always deeply confused by people who think all medicine is "just repeat whatever ChatGPT said as if it's profound, like, duh - I'm smart and invincible and can't quite figure out that other people aren't me", in spite of them not knowing anything about medicine in the first place.

      • brandonmenc 1 hour ago
        Because I’ll know how much I can slack off.
      • oortoo 13 minutes ago
        Because people are lazy enough that they will pay money to be told they need to stop being lazy lmao
      • jpalawaga 57 minutes ago
        apob and lpa i believe are relatively stable even outside of diet.
        • brandonb 47 minutes ago
          Lp(a) is stable since it's mostly genetically determined.

          ApoB is very responsive to diet and medication--you can lower it by about 85%.

          • devin 38 minutes ago
            ApoB is no doubt responsve to medication, but my understanding is that diet and exercise can't get anywhere close to achieving that 85% number.
    • RobotToaster 52 minutes ago
      Anyone know of companies in the UK that offer this kind of testing inexpensively?
  • dubeye 1 hour ago
    This is a little bit misleading.

    'Preventing a heart attack' means taking life long medication to reduce the risk of heart attack by about 1%, which is worth doing, but complicates the maths a little bit. The scan doesn't magically make you healthy or 'much' less likely to have a heart attack

    • devin 43 minutes ago
      Sources? That 1% number is in my understanding wildly incorrect for statins, if that's what you're referring to. Are you comparing use of statins for people who already are low risk for heart attack over the next 10 years?
    • aardvarkr 43 minutes ago
      By one percent, do you mean 3% of people per year in a high risk category turns into 2.97%, or 2%? Because that’s a big difference
      • dubeye 30 minutes ago
        It is a big difference and definitely worth doing
  • flerchin 2 hours ago
    The argument made in the article seems inarguable, but I don't see how a coronary artery calcium score is going to prevent a heart attack. You gotta do statins, exercise, and eat right basically no matter what. FWIW I had a coronary artery calcium score ordered by my doctor at my last checkup. It was $120.
    • minkeymaniac 1 hour ago
      I assume they mean.. have the test and then act upon it with diet/exercise/medicine to prevent the heart attack If you never had the test, maybe you don't know you are at risk and don't make any changes and then you get the heart attack
      • wrs 1 hour ago
        It’s also not just a “treat or not” decision. I have a family history and high test results so was already treating on the assumption I’m high-risk, but the scan revealed that we needed to be more aggressive. (And hopefully in a few years a scan will show we’re reversing the progression.) Personal data is always better than population data for treatment decisions.
  • faangguyindia 1 hour ago
    Same for diet and exercise.

    They'll use flawed research to claim diet and exercise don't work for obesity, then the general public uses that research and claims, "Diet doesn't work for fat people."

    Soon, everyone is convinced every guy with a trivial amount of weight to lose needs to be on GLP-1s.

    • paxy 1 hour ago
      > They'll use flawed research to claim diet and exercise don't work for obesity

      Who is "they"? Who is saying this?

    • thinkingtoilet 1 hour ago
      I've never ever heard anyone say diet and exercise don't work. Is this something a real person has said to you in real life? Not on the internet?
      • WarmWash 1 hour ago
        I have known at least two people, who while not making the claim that it doesn't work, do make the claim that it doesn't work for them.

        To me this is just subconscious denial/defending of their food addiction.

        • jmull 29 minutes ago
          Diet and exercise tells people what to do, but not how to do it.

          Knowing that you should do something, doesn't necessarily mean can do it. There's still the question of exactly how.

          E.g., diet is heavily influenced by hormones/hormonal cycles and access to quality food choices, which vary significantly between people. The glp1s available now are a big help with the hormonal part of this, but they are not within reach of a large proportion of people.

          > To me this is just subconscious denial/defending of their food addiction.

          If you have to make up unobservable phenomena to explain plainly visible facts, it's usually a sign to look for a different overall model.

          • WarmWash 1 minute ago
            Trust me, these people aren't broke and uneducated. They're white collar upper middle class. You don't have to apologize for them
        • triceratops 1 hour ago
          Ok but if they acknowledge it's an addiction, that's still a medical issue requiring treatment. Maybe that means going to food addiction anonymous meetings but if GLP-1 is like methadone for food, why not do it?
          • WarmWash 52 minutes ago
            No, they don't acknowledge it. To them their body is different and being large is just how it is.
          • thinkingtoilet 1 hour ago
            If you are in a place where you truly can't control your habits then of course GLP-1s are an amazing tool. However, if you don't adjust your life-style you will relapse when you get off, so the real solution is to adjust your life style. Also, there are benefits to exercise that aren't connected to losing weight. In my experience, 100% of the people I know on GLP-1 drugs are not exercising. I'm sure I'll get 1000 responses of people who do, but in my experience they don't. So you put yourself in a position where you're not addressing the actual problem, you are on a drug for life, and you aren't being healthy in other capacities. Are there times where these drugs make sense? Yes. Of course. Spare me the lecture. Everyone I know on these drugs are middle class people who absolutely could be healthy but don't want to put in any work.
            • Shitty-kitty 49 minutes ago
              Exercise does very little for weight-loss. You can fill up on calories far faster then you can exercise them.
      • RobotToaster 35 minutes ago
        It's something I've read a few times. Most of the studies I've seen say it's effect is modest at best. At least if it was a drug there wouldn't be enough evidence for it to get FDA approval (especially with all the "side effects" such as injury)

        Arguably this is a limitation on how the studies were done, as nobody is going to pay for extensive studies since you can't patent exercise.

      • tripleee 1 hour ago
        I hear this all the time to the point where I don't even mention looking at a person's diet and exercise because I expect they'll be shot down
      • add-sub-mul-div 1 hour ago
        Bodies are all different. Diet and exercise can work for one person and not another. But the type of person who wants to believe all fat people are slothful, all unemployed people are lazy, and so on, will invent in bad faith the straw man argument that we think diet and exercise do not work at all. They're not worth engaging with.
        • thinkingtoilet 28 minutes ago
          Incorrect. There is no person a diet and exercise won't work for. You can not run a caloric deficit and gain weight. The laws of physics apply here.
  • hansonkd 32 minutes ago
    This is the ultimate case for AI. Intelligence is partly scored based on predictions/planning, so if AI is really intelligent it should be able to tell what remediations are worth it and then lower your insurance cost based on following its recommendations. and back it up by backing those premiums itself.

    Home insurance can benefit from this too. I just got a quote on a property i looked at with a $20k/yr premium, partly because of being in CA with a slope and age of the property.

    At $20k/yr, there should be some economic way of an insurance company essentially saying "instead of $20k a year in premiums, here is a $300,000 30 year loan to do preventive measures on the property, and if you do them, your policy will drop to a more normal $3k/yr" or something along those lines.

  • mchusma 38 minutes ago
    You should also just pay $100 yourself? I think the bigger issue is just ease. They should deregulate these so they are simple to get
    • wat10000 27 minutes ago
      Is regulation an obstacle here? From a quick search it appears you can just find a place that performs these scans and book an appointment.
    • jmyeet 33 minutes ago
      I really can't believe there's anyone left who thinks deregulation solves anything. Everywhere it's tried it is a demonstrable failure. It's just an excuse for an uptick in profits at the expense of safety, the environment, etc.

      Safety regulations are written in blood. They exist because people died because the industries could not and cannot be trusted to regulate themselves.

      The most generous interpretation is that people conflate regulation with rent-seeking. These are two entirely different things.

  • Noaidi 28 minutes ago
    I have been disabled on medicare for 23 years. I have often told my doctors that if they spent the time and money to look at my biology more closely it would have saved the tax payers so much money from medicare and likability payments.

    Health care is actually sick care.

    I obviously have a genetic condition because it runs through my mothers side of my family, but they refuse to look at my genetics. So, did. I found things. I begged a researcher to test me for a special sort of immune deficiency (ADA Deficiency) . The tests shows I have a partial immune deficiency. I showed it to my doctor and nothing.

    When my condition flares up (Too mush ATP and GTP) it effects my brain and nervous sytem and I have to be institutionalized. Five times now. I keep telling them my mood problem is caused by an immune deficiency but now one cares.

    Sorry, end of rant.

  • declan_roberts 1 hour ago
    We are getting very close to this with cheaper and cheaper glp-1 drugs. Soon they'll be free for any overweight American.
    • mythrwy 1 hour ago
      I have to wonder what the longer term consequences of modifying peoples essential biological drives chemically will turn out to be in the long run.

      That isn't to say this might not be the best solution for many people but I still wonder.

      • Shitty-kitty 54 minutes ago
        The biological drive for high calorie food and fat reserves are the problem in a environment where food-scarcity is not an issue.
      • ryandrake 51 minutes ago
        I guarantee the Unhealthy Snack Industry has their top scientists hard at work trying to find some kind of formula to make people on GLP-1 drugs go back to craving the soda and doritos.
  • fastaguy88 6 minutes ago
    Good luck getting any kind of scan from your doctor/hospital for $100.
  • peter_d_sherman 10 minutes ago
    Prevention Vs. Cure...

    (aka Proactive Vs. Reactive)

    ((aka Present Responsibility Vs. Future Response))

    "An ounce of Prevention is worth a pound of Cure" (as the old expression goes...)

    Observation: Most health insurance policies today, whether they are government or private corporation, national or regional, are based on the idea of paying for medical/health problems AFTER the onset of the health problem...

    Prevention, preventative health, preventative medicine, and preventative programs -- would not only do a lot to preempt future health problems, but it would also save a ton of money (a ton of taxpayer money if the health insurance is a government sponsored one), as the above article so eloquently makes clear!

    Observation: Some insurance policies do include some preventative health aspects -- but as medicine is complex and there are always new discoveries, there is always another step up, another higher level in what could be delivered...

    In other words, these could always be improved...

    "An ounce of Prevention is worth a pound of Cure."

    Anyway, great article!

  • tkdb 1 hour ago
    Insurance was invented to pay for emergencies. Your home insurance doesn't pay to perform routine maintenance on your roof, but neither will it pay to repair "normal" wear and tear. Your home insurance pays when a tree falls on your roof.

    Our healthcare system has co-evolved with insurance in a sort of partial free-market, partial heavily regulated environment. Arguably we get the worse parts of both: Kafka-esque beaurocratic mazes and shareholder value optimization for private firms.

    There's a paradigm shift needed in how health insurance works: optimize for total cost of care.

    Can the invisible hand do this when providers are offering mainly treatments with token preventative care visits thrown in?

    • longerthoughts 48 minutes ago
      >There's a paradigm shift needed in how health insurance works: optimize for total cost of care.

      You're criticizing health insurance but payers are far more incentive-aligned with patients on lowering total cost of care than the providers. They carry the risk and have to pay out claims. Providers, on the other hand, have an incentive to provide lots of expensive reactive care that's bound to expensive labor.

      I agree with the sentiment of your "only for emergencies" point and wish direct care was more affordable. The problem is providers charge insanely high rates for services because a) they can get payers to cover it, and b) they're covering the cost of labor that's getting increasingly expensive with no commensurate increase in productivity [0].

      For prices to come down substantially in the US, we'd need a much greater supply of doctors or more automated care. The former is against the financial interests of current doctors and the latter is an uphill battle against FDA regs, state medical boards, and billing codes from CMS to make it reimbursable.

      [0] https://en.wikipedia.org/wiki/Baumol_effect#Healthcare

    • myersj 28 minutes ago
      > There's a paradigm shift needed in how health insurance works: optimize for total cost of care.

      Value-based care, e.g. Medicare Advantage.

      The idea is that the government gives you $X for the care of a patient, with multipliers on risk factors. The government's goal is for that to be basically exactly what care costs. The provider is incentivized to treat you for less. Which sounds perverse, but if they, for instance, deny all care, a patient will end up in the hospital and cost exponentially more than they would have through proper preventive care. It is not perfect, and it should be broader, but it is a strong optimizer for providing the right care to keep a patient healthy, without providing hundreds of unnecessary tests (and especially imaging) that are medically unnecessary.

      It is absolutely a system that should be rolling out to more and more patients.

  • TZubiri 1 hour ago
    I'm interested in this intersection of technical problems where we already have the tech to solve it, but the bottlenecks are social/legal/financial incentive.

    Recently there was an old lady in the family that had an appendicitis, an ambulance rejected her, and the next day it got worse, and at that point she was accepted, but it was a bit too late.

    One hypothesis is that triaging is hard and there's a lot of demand so things only go in when it's bad enough (considering there was medical insurance, they aren't charging per patient, so there's no incentive to take on more patients). But if that were the case, then preventive measures would actually reduce the total burden on their system.

    The more cynical hypothesis that I'm holidng is that that health system is maximizing for work, if there's 10 appendicitis per month, and they are all handled in time, that's maybe like 5 hours of billable hours per patient? But if the appendicitis becomes bad enough and there's a puncture, then you have infections, complications, the patients have to stay for weeks and often come back for checkups, we are looking at maybe 100 billable hours? So the financial incentive is there.

    In that sense what I want to add is that the title would be completely wrong, the solution is not for the hospital to pay 100$ for prevention, but for prevention to be more accurately priced, we should be paying 50k, and maybe even 100k for prevention, because we value it more than emergency action.

    In a broader economic sense, there's a lot of cases where there's a huge difference between the cost and the value, Shkreli got a lot of heat for surging up medicine prices, but I don't think it's immediately obvious that something should be valued in proportion to what it costs. Maybe if we price heart prevention at 100K, there would be more incentive for everyone involved to just get a fucking pill to those in need, imagine how many people would jump at that opportunity to make it happen, call centers, bureocrats, NOC support, legal teams, all dedicated to making sure a pill gets to the patient before a heart attack does.

    • wrs 1 hour ago
      Nobody likes to say this out loud, but because the US healthcare system is largely based on “fee for service” billing, it is true by definition that the sicker the patients are, the more profit the providers make. So incentives for actually making people healthier have to be imposed in indirect ways.

      There are some pockets of “per capita” payment, where the provider gets a fixed amount per person and is thus encouraged to reduce treatment costs, which indirectly should encourage preventative care, but also encourages just refusing to treat people.

      We could remove these weird constraints by making health care a government service rather than a highly contorted pseudo-market, but that would not be the American way. It has to at least look like a market, even if it’s an ineffective, inefficient, opaque, corrupt one.

      • myersj 22 minutes ago
        > We could remove these weird constraints by making health care a government service rather than a highly contorted pseudo-market, but that would not be the American way. It has to at least look like a market, even if it’s an ineffective, inefficient, opaque, corrupt one.

        It is still a market (and a single-payer one, ultimately) in these places, but it is not a government service. It is the best solution: the government funds the appropriate cost of care, the provider group is financially responsible for meeting it, and they are incentivized directly to get it right.

        The left needs to stop shrieking about Medicare-for-all and the right needs to stop pretending like it can even spell healthcare. There are good solutions.

        > but also encourages just refusing to treat people.

        It categorically does not. It would be foolish to do so.

        • longerthoughts 2 minutes ago
          >It categorically does not. It would be foolish to do so.

          Foolish hardly implies categorically false. It's a well-documented incentive for other risk-bearing entities (see insurance claim denials). Why are providers under capitated contracts categorically immune to refusing treatment to protect margins?

      • longerthoughts 24 minutes ago
        Completely agree with your characterization of the current system but why does making healthcare a government service necessarily lead to better outcomes vs current state or a more sensibly constrained market?

        Seems obviously right in terms of total cost to the median patient (less obvious for individuals in higher tax brackets), so I'm not disputing that. More curious about incentives to improve care delivery for better long-term outcomes.